Last update
3/16/2026

Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Moderately Good
Based on 21 Reviews
7.9
Supplement Facts
Serving Size: 1 Caplet
Amount Per Serving
%DV
Organic ashwagandha powder (root)(0.2% Withanolides, 0.76 mg)
380 mg
*
Organic ashwagandha extract (root)(0.5% Withanolides, 1.4 mg)
280 mg
*
Organic ashwagandha supercriticalCO2 extract (root) (Withania somnifera) (8% Withanolides, 0.8 mg)
10 mg
*
📅 Last updated:

Top Medical Research Studies

9
Essential fatty acids aid fatigue syndrome
We conducted a study to evaluate the effectiveness of essential fatty acids, particularly docosahexaenoic acid (DHA), in treating postviral fatigue syndrome, which affects many individuals after a viral infection.

In a double-blind, placebo-controlled setup involving 63 adults, we administered a mixture of essential fatty acids to half of the participants while the other half received a placebo. Each person received eight capsules daily for three months, and we checked their overall condition, fatigue, and other symptoms at various points throughout the study.

Excitingly, we observed significant improvements among those taking the active treatment. After just one month, 74% of participants in the DHA group felt better compared to only 23% in the placebo group. That number rose to 85% at the three-month mark, indicating that while the placebo group reverted to their initial state, those receiving essential fatty acids continued to improve.

Additionally, we saw that the fatty acid levels in patients’ blood cells normalized with treatment, and there were no adverse effects reported. Overall, our findings suggest that DHA, as part of a broader essential fatty acid approach, is a safe and beneficial option for those suffering from postviral fatigue syndrome.
Read More
7
Link Between Omega-3 and CFS
We explored the connection between omega-3 polyunsaturated fatty acids (PUFAs), particularly docosahexaenoic acid (DHA), and chronic fatigue syndrome (CFS). In this study, researchers compared serum PUFA levels in 22 patients with CFS to 12 healthy controls.

Their findings revealed that CFS patients had higher levels of omega-6 fatty acids and lower omega-3 levels compared to those without the condition. Specifically, the ratio of omega-3 to omega-6 was significantly lower in CFS patients. This imbalance was correlated with more severe symptoms, such as fatigue and memory problems. The research also suggested that lower zinc levels might be linked to this imbalance and indicate problems with T cell activation, which plays an essential role in immune function.

While the study provides insights into the relationship between omega-3 fatty acids and CFS, it focuses on omega-3s in general and does not isolate the effects of DHA alone. However, it hints that increasing omega-3 PUFA intake, including DHA, could potentially help manage symptoms of CFS, even though further research is needed to confirm this finding.
Read More

Most Useful Reviews

9
Improved vitality
1 people found this helpful
This product has notably enhanced my energy levels and overall health. After consistent use, I found a marked increase in stamina and a decrease in fatigue. Taking it in the morning helps me stay active and boosts my quality of life. Overall, it’s a product I would recommend.
Read More
9
Effective improvement
1 people found this helpful
This product is highly effective in improving fatigue!
Read More
9
Surge of strength
1 people found this helpful
Excellent! I recently began taking this, and I feel an impressive surge of energy with less fatigue. I’ve not experienced side effects. I consume it in the morning, approximately 40 minutes before meals. A natural product indeed.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
  • All Researches
9
Essential fatty acids aid fatigue syndrome
We conducted a study to evaluate the effectiveness of essential fatty acids, particularly docosahexaenoic acid (DHA), in treating postviral fatigue syndrome, which affects many individuals after a viral infection.

In a double-blind, placebo-controlled setup involving 63 adults, we administered a mixture of essential fatty acids to half of the participants while the other half received a placebo. Each person received eight capsules daily for three months, and we checked their overall condition, fatigue, and other symptoms at various points throughout the study.

Excitingly, we observed significant improvements among those taking the active treatment. After just one month, 74% of participants in the DHA group felt better compared to only 23% in the placebo group. That number rose to 85% at the three-month mark, indicating that while the placebo group reverted to their initial state, those receiving essential fatty acids continued to improve.

Additionally, we saw that the fatty acid levels in patients’ blood cells normalized with treatment, and there were no adverse effects reported. Overall, our findings suggest that DHA, as part of a broader essential fatty acid approach, is a safe and beneficial option for those suffering from postviral fatigue syndrome.
Read More
7
Link Between Omega-3 and CFS
We explored the connection between omega-3 polyunsaturated fatty acids (PUFAs), particularly docosahexaenoic acid (DHA), and chronic fatigue syndrome (CFS). In this study, researchers compared serum PUFA levels in 22 patients with CFS to 12 healthy controls.

Their findings revealed that CFS patients had higher levels of omega-6 fatty acids and lower omega-3 levels compared to those without the condition. Specifically, the ratio of omega-3 to omega-6 was significantly lower in CFS patients. This imbalance was correlated with more severe symptoms, such as fatigue and memory problems. The research also suggested that lower zinc levels might be linked to this imbalance and indicate problems with T cell activation, which plays an essential role in immune function.

While the study provides insights into the relationship between omega-3 fatty acids and CFS, it focuses on omega-3s in general and does not isolate the effects of DHA alone. However, it hints that increasing omega-3 PUFA intake, including DHA, could potentially help manage symptoms of CFS, even though further research is needed to confirm this finding.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 21 Reviews
7.9
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Improved vitality
1 people found this helpful
This product has notably enhanced my energy levels and overall health. After consistent use, I found a marked increase in stamina and a decrease in fatigue. Taking it in the morning helps me stay active and boosts my quality of life. Overall, it’s a product I would recommend.
Read More
9
Effective improvement
1 people found this helpful
This product is highly effective in improving fatigue!
Read More
9
Surge of strength
1 people found this helpful
Excellent! I recently began taking this, and I feel an impressive surge of energy with less fatigue. I’ve not experienced side effects. I consume it in the morning, approximately 40 minutes before meals. A natural product indeed.
Read More
7.5
Stress resistance
1 people found this helpful
I bought this product as managing full-time work was becoming challenging. It helps me become more resilient to stress and reduces my daily fatigue significantly. I usually consume it when feeling tired, but I always keep it on hand for reassurance.
Read More
9
Increased energy levels
Feeling fatigued? If you suffer from fatigue, try these! I have tried other brands, but these are amazing! They can be almost too strong, giving me excessive energy, so I sometimes cut back to half a tablet as I am sensitive. I suffer from fibromyalgia and Chronic Fatigue Syndrome, and these really helped! I now have so much energy and feel more human than ever! Additionally, they enhance my overall feeling and assist with anxiety. I love these!
Read More

Frequently Asked Questions

7.5
Relieved my fatigue
1 people found this helpful
Great quality; it effectively relieves my chronic fatigue syndrome. I used it for two weeks and found it beneficial. If you found my comment helpful, please press yes.
7.5
Needs continuous intake
3 people found this helpful
My high cortisol levels affect my health, causing constant stress and fatigue. After taking the course, my overall condition improved for about two weeks. However, I feel stressed again, so I need to continue the course until stable results are achieved, along with adding omega supplements.
9
Improved vitality
1 people found this helpful
This product has notably enhanced my energy levels and overall health. After consistent use, I found a marked increase in stamina and a decrease in fatigue. Taking it in the morning helps me stay active and boosts my quality of life. Overall, it’s a product I would recommend.
9
Surge of strength
1 people found this helpful
Excellent! I recently began taking this, and I feel an impressive surge of energy with less fatigue. I’ve not experienced side effects. I consume it in the morning, approximately 40 minutes before meals. A natural product indeed.
7.5
Higher energy levels
4 people found this helpful
At 70 years old, I take Ashwagandha for arthritis and stress. An added bonus is my increased energy levels, allowing me to accomplish more daily with less fatigue. I’m very pleased my nutritionist recommended it. I've taken it daily for about three months with no adverse side effects; nothing but positive things to say about this herb.
2
Did not provide relief
2 people found this helpful
Unfortunately, it did not work for my husband's chronic fatigue syndrome, as he complains of fatigue by the evening. The underlying reason seems deeper.
7.5
Effective for stress fatigue
Recommended by a YouTuber, it seems effective for my stress fatigue related to chronic fatigue syndrome.
7.5
Steady energy
1 people found this helpful
This is an excellent brand with outstanding quality. It appears to help reduce stress and fatigue, ensuring my energy levels remain steady throughout the day. I take it with my breakfast. If taken later, it can make me overly alert at night. Prompt shipping and much more affordable from iHerb compared to other online stores.
7
Link Between Omega-3 and CFS
We explored the connection between omega-3 polyunsaturated fatty acids (PUFAs), particularly docosahexaenoic acid (DHA), and chronic fatigue syndrome (CFS). In this study, researchers compared serum PUFA levels in 22 patients with CFS to 12 healthy controls.

Their findings revealed that CFS patients had higher levels of omega-6 fatty acids and lower omega-3 levels compared to those without the condition. Specifically, the ratio of omega-3 to omega-6 was significantly lower in CFS patients. This imbalance was correlated with more severe symptoms, such as fatigue and memory problems. The research also suggested that lower zinc levels might be linked to this imbalance and indicate problems with T cell activation, which plays an essential role in immune function.

While the study provides insights into the relationship between omega-3 fatty acids and CFS, it focuses on omega-3s in general and does not isolate the effects of DHA alone. However, it hints that increasing omega-3 PUFA intake, including DHA, could potentially help manage symptoms of CFS, even though further research is needed to confirm this finding.
9
Essential fatty acids aid fatigue syndrome
We conducted a study to evaluate the effectiveness of essential fatty acids, particularly docosahexaenoic acid (DHA), in treating postviral fatigue syndrome, which affects many individuals after a viral infection.

In a double-blind, placebo-controlled setup involving 63 adults, we administered a mixture of essential fatty acids to half of the participants while the other half received a placebo. Each person received eight capsules daily for three months, and we checked their overall condition, fatigue, and other symptoms at various points throughout the study.

Excitingly, we observed significant improvements among those taking the active treatment. After just one month, 74% of participants in the DHA group felt better compared to only 23% in the placebo group. That number rose to 85% at the three-month mark, indicating that while the placebo group reverted to their initial state, those receiving essential fatty acids continued to improve.

Additionally, we saw that the fatty acid levels in patients’ blood cells normalized with treatment, and there were no adverse effects reported. Overall, our findings suggest that DHA, as part of a broader essential fatty acid approach, is a safe and beneficial option for those suffering from postviral fatigue syndrome.

References

  1. Maes M, Mihaylova I, Leunis JC. In chronic fatigue syndrome, the decreased levels of omega-3 poly-unsaturated fatty acids are related to lowered serum zinc and defects in T cell activation. Neuro Endocrinol Lett. 2005;26:745. PubMed
  2. Behan PO, Behan WM, Horrobin D. Effect of high doses of essential fatty acids on the postviral fatigue syndrome. Acta Neurol Scand. 1990;82:209. PubMed
Data last updated:
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